The first review I've seen (book not out until October 2008) says--
"Marc Estrin discovers that another writer's novel - The Nose - not only has spawned a bizarre cult among the nation's youth but also is based on the extraordinary life of a real person - an outcast named Alexei Pigov...On the left handed page of The Annotated Nose we read The Nose itself, and take in the beautifully unsettling illustrations of Delia Robinson. On the right-hand page we follow Alexei's complaints - always surprising and often far reaching.
I've never heard of anything like this and the illustrations are stunning. It sounds like a most unusual literary experiment - must be checked out."